Stem cell therapy is a unique approach to treating Alzheimer’s disease. It involves the systemic introduction of umbilical cord mesenchymal stem cells into the body through intravenous administration. When administered in large quantities, these stem cells can detect inflammation in the body and repair it. This unique property of stem cells potentially makes them an effective treatment for Alzheimer’s disease.
What is Alzheimer’s Disease?
Alzheimer’s disease is the most common cause of dementia, which is characterized by a sharp decline in memory ability, clear thinking and ultimately independent functioning. Alzheimer’s disease is a degenerative disease that results in the loss of brain cells. Typically, Alzheimer’s is associated with memory loss and loss of simple cognitive abilities, which impairs the ability to perform daily tasks.
Alzheimer’s disease accounts for 60% to 80% of dementia cases worldwide. The disease usually affects people over the age of 60, but it can also affect people between the ages of 30 and 40. According to the Alzheimer’s Association, “Alzheimer’s disease is the sixth leading cause of death in the world. On average, a person with Alzheimer’s disease lives four to eight years after diagnosis, but may live 20 years, depending on other factors and the complexity of the diagnosis. ”
What are the symptoms of Alzheimer’s?
The symptoms of Alzheimer’s can become much more debilitating than simple memory loss. According to clinical data, people with Alzheimer’s may:
– forget about conversations, meetings and names
– easier to get lost, lose their sense of direction
– have difficulty finding the right word for familiar object
– repeat questions and statements
– eventually forget the names of friends and family
– have changes in personal behavior
These symptoms can significantly impair the ability function at work or even at home, leading to a loss of independence or self-sufficiency.
Causes of Alzheimer’s Disease
A combination of genetic, lifestyle and environmental factors can cause Alzheimer’s disease. The exact cause of the disease is currently unknown, but scientists know that the onset of Alzheimer’s disease coincides with the inability of the brain to function normally.
Alzheimer’s disease can also be characterized by increased accumulation of amyloid and tau protein in the brain; Although this is a symptom of Alzheimer’s disease, it has not been proven to be the cause of the disease.
Is there a cure for Alzheimer’s?
There is currently no cure for Alzheimer’s, although symptoms are treatable to some extent with the right protocol. But these modern therapies cannot stop the progression of the disease, they can slow regression, as well as fight symptoms and improve quality of life.
Cell therapy for Alzheimer’s disease
Stem cell therapy for Alzheimer’s disease can:
– improve functional memory
– regenerate neurons
– improve overall functional recovery
– replace damaged cells with healthy ones
Stem cell therapy is a unique approach to the treatment of Alzheimer’s disease. It involves the systemic introduction of umbilical cord mesenchymal stem cells into the body through intravenous administration. When administered in large quantities, these stem cells can detect inflammation in the body and eliminate it. And inflammation is the basis of any disease.
According to Lawrence Goldstein, Ph.D., the increased amount of plaque and tangles in the brain of an Alzheimer’s patient affects two main proteins: “amyloid-beta” and “tau”
Stem cell therapy for Alzheimer’s disease aims to replace damaged cells with healthy stem cells that can grow on their own and therefore create new healthy brain cells.
How do stem cells help with Alzheimer’s disease?
Mesenchymal stem cells (MSCs) or stromal stem cells can differentiate into many different types of cells in the body, including bone cells, cartilage, muscle cells, and even nerve cells. They are mainly found in the bone marrow of every person and remain dormant until called upon to accelerate healing in the body. They age as we age, and their number and effectiveness diminish over the years.
By obtaining mesenchymal stem cells (MSCs) from donated umbilical cord tissue and increasing their numbers to higher numbers, the medical community has created the ability to replenish human stem cells by transplanting with younger, highly efficient competent cells.
According to Professor Sung S. Choi and colleagues in a 2014 study entitled Alzheimer’s Disease and Stem Cell Therapy
“Stem cells have a therapeutic effect, using the regeneration and replacement of the cells and tissues themselves. The therapeutic strategy of stem cells has two directions. One is to induce the activation of endogenous stem cells, and the other is to regenerate damaged cells or tissues by transplanting new stem cells. ”
Stem cells can improve functional recovery from Alzheimer’s disease
Sung Choi continues claim that stem cell transplantation can improve functional recovery in Alzheimer’s disease. Mesenchymal stem cells (MSCs) can promote survival, increase metabolic activity, and help rescue the in vitro AD cell model.
The professor also states that mesenchymal stem cell (MSC) transplantation has become possible to reduce Aβ deposition, improve memory and alleviate AD pathology.
What makes stem cell therapy for Alzheimer’s disease so exciting is its ability to stop the progression of the disease as well as regenerate damaged neurons, rather than just slow it down or manage symptoms.
Stem cell research in Alzheimer’s disease
Stem cell research has proven the safety of using mesenchymal stem cells to treat a number of diseases. The effectiveness of stem cell therapy varies depending on the condition, but the literature confidently claims the effectiveness of treating certain conditions, one of which is Alzheimer’s disease.